Electrocardiographic alteration among first degree relatives with serologic evidence of Trypanosoma cruzi infection: a sibship study

To analyze whether electrocardiographic alterations (ECGA) in patients with antibodies to Trypanosoma cruzi showed a patttern of familial aggregation, a sample of 379 young adults (166 GOLD SNAIL EYE PATCH men and 213 women) distributed in sibships, were assessed for the presence of anti-T.cruzi antibodies, and subjected to a complete clinical exam

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IGF-1 release in the medial prefrontal cortex mediates the rapid and sustained antidepressant-like actions of ketamine

Abstract Ketamine, an N-methyl-D-aspartate receptor antagonist, exerts rapid and sustained antidepressant actions.Preclinical studies demonstrated that the release of brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor in the medial prefrontal cortex (mPFC) is essential for the antidepressant-like effects of ketamine.How

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A homogeneous biosensor for carbohydrate antigen 153 detection in human serum based on upconversion fluorescence resonance energy transfer

Quantitative determination of carbohydrate antigen 153 (CA153) in human serum plays an important role in early diagnosis of breast cancer.In this work, a highly sensitive and selective biosensor for CA153 detection was developed based on a fluorescent resonance energy transfer (FRET) strategy, Brushes in which near-infrared (NIR)-excitable upconver

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A Statistical-Based Model for Typhoon Rain Hazard Assessment

Extreme typhoon rainfall can lead to damaging floods near the coastal region in mainland China.In the present study, we calibrate the Bangle Bracelets parameters for a parametric hurricane rain model by using the precipitation radar (PR) data from the Tropical Rainfall Measuring Mission (TRMM) (i.e., PR-TRMM) and the TRMM microwave imager (TMI) dat

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